Does Your Gout Flare Often? IV Infusion Therapy May Be the Next Best Step

If you live with gout, you know the pain is more than a minor nuisance. It’s a searing, burning sensation that can stop you in your tracks. A flare can wake you from your sleep or interrupt a productive work day.  

When flares become frequent or intense, it's time to look beyond the basics for better relief. That’s where intravenous (IV) infusion therapy may offer the support that can make a major difference.

Gout is a painful form of inflammatory arthritis that occurs when uric acid accumulates in the bloodstream and forms sharp crystals in the joints. These crystals trigger sudden, very painful attacks of swelling, redness, and tenderness, most commonly in the big toe, but other joints can be affected too.

While diet and oral medications help many people manage gout, they don’t provide full relief for everyone. 

At Comprehensive Arthritis Care in Hendersonville, Tennessee, Mohammad F. Ali, MD, and our team understand how frustrating repeat gout attacks can be. Our practice offers advanced care, including in-house infusion therapy, to help you feel better and stay active.

Our team is dedicated to partnering with our patients and finding solutions that preserve joint function and quality of life.

Why gout becomes difficult to control

Uric acid levels rise in your bloodstream due to various factors, including diet, genetics, kidney function, or other underlying health issues. When uric acid crystallizes, it leads to inflammation and joint damage if left untreated. Most patients start with oral medications to either lower uric acid or reduce inflammation during flares.

However, if you continue to experience frequent attacks despite lifestyle changes and standard medications, your gout may be classified as refractory. This means the disease isn’t responding well to typical therapy, and it may require a more aggressive treatment strategy.

How IV infusion therapy can help

IV infusion therapy delivers medication directly into your bloodstream, allowing for faster and more potent results. In cases of gout, the most commonly used infusion treatment is Pegloticase (Krystexxa®), an enzyme therapy that breaks down uric acid so your body can eliminate it more effectively.

Pegloticase is typically given every two weeks and is reserved for patients whose gout hasn’t responded to other medications. It’s particularly effective in reducing uric acid levels quickly, helping to dissolve existing crystals and prevent new ones from forming. This can lead to fewer flares, less joint damage, and improved overall function.

What to expect from infusion therapy

Comprehensive Arthritis Care offers on-site infusion therapy in a relaxed, well-equipped setting. You’ll receive treatment in a comfortable recliner, with access to Wi-Fi to make your visit more enjoyable. Our infusion team monitors each session to ensure your safety and comfort.

Before starting infusion therapy, Dr. Ali performs lab work and conducts a full evaluation to determine whether you're a candidate for this type of treatment. If Pegloticase is appropriate, our team discusses with you what you can expect and how to prepare for each appointment.

Don’t wait for flares to become disabling

If gout is interfering with your daily life, it's time to explore more targeted treatment. IV infusion therapy could offer more effective relief, especially if traditional options fall short.

Contact us at our Hendersonville office today to schedule an evaluation with Dr. Ali and learn whether infusion therapy could be the next step in managing your gout. Let’s get you back to living with less pain and more movement.