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4 Early Signs of Systemic Sclerosis

May 08, 2025
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Scleroderma affects people of all age groups. Rheumatologists assist patients in staying as healthy as possible with strategies that include IV infusion therapy to ease inflammation, improve symptoms, and reduce complication risk.

Systemic sclerosis, also known as scleroderma, is a complex autoimmune disease that can affect the skin, joints, and internal organs. Because it can develop slowly and mimic other conditions, early detection is crucial. 

Comprehensive Arthritis Care in Hendersonville, Tennessee, is committed to helping patients manage and live well with rheumatic diseases such as systemic sclerosis, and this includes recognizing the earliest signs. Detecting systemic sclerosis early provides an opportunity for medical intervention to reduce the risk of serious complications.

Early management provides the best chance at protecting your organs, preserving mobility, and living well.

Here are four early signs of systemic sclerosis you shouldn’t ignore:

1. Skin tightening or hardening

Skin changes are one of the hallmark signs of systemic sclerosis. You might notice areas such as the fingers, hands, or face becoming tight, shiny, or thick. This happens because of excess collagen production, which leads to hardening of the skin. 

It may start subtly, but over time, it can limit flexibility and make everyday movements more difficult. If your skin starts to feel tighter, tougher, or less elastic, it’s best to get checked out.

2. Raynaud’s disease

Raynaud’s disease is often one of the earliest and most noticeable symptoms. It causes your fingers or toes to turn white or blue in response to cold or stress due to narrowed blood vessels. 

While Raynaud’s can occur on its own, it’s also a strong red flag for systemic sclerosis, especially if you’re experiencing other symptoms like skin changes or joint stiffness. Frequent Raynaud’s episodes, particularly if they’re painful or severe, warrant a conversation with a rheumatologist.

3. Joint pain or stiffness

Many people with systemic sclerosis first report joint pain, swelling, or stiffness. This is often mistaken for typical aging or early arthritis. But if you’re waking up with stiff joints that take longer to loosen, or if you notice pain in your fingers, wrists, or other small joints, this could be a sign that inflammation is at play. 

Over time, unchecked inflammation can lead to joint damage. Early evaluation and management can make a real difference in preserving function.

4. Digestive problems

Systemic sclerosis frequently affects the gastrointestinal system. You may experience symptoms such as frequent heartburn, difficulty swallowing, bloating, or a sense of fullness after eating small servings. These symptoms occur when the disease affects the muscles in the esophagus or intestines, resulting in sluggish digestion.  

Managing systemic sclerosis with IV infusion therapy

IV infusion therapy is an effective tool in managing systemic sclerosis, especially for patients with moderate-to-severe symptoms or organ involvement. 

For systemic sclerosis, infusions may include immunosuppressive medications like cyclophosphamide or biologics that help control inflammation and slow disease progression. In some cases, medications are used to manage specific complications, such as pulmonary fibrosis or vascular issues. 

At Comprehensive Arthritis Care, IV infusion therapy is administered on-site in a comfortable, patient-centered setting. Our infusion suite features reclining chairs and high-speed Wi-Fi to make the experience as pleasant as possible. 

Our team monitors patients closely throughout each session to ensure safety and effectiveness. We work with each individual to determine if infusion therapy is the right option for you. 

Expert systemic sclerosis management

If you’re noticing any of these symptoms, or if you have any related concerns, our board-certified rheumatology team offers comprehensive evaluations, in-office testing, and advanced treatment options designed to help you manage symptoms and protect your health.

We’re proud to serve the Hendersonville and greater Sumner County communities with personalized, expert care. Call our office, or book online for this and all of your rheumatic care needs.